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Phenotypes Associated with This Genotype
Genotype
MGI:4358484
Allelic
Composition		 Il2rgtm1Cgn/Il2rgtm1Cgn
Kittm1.1Bsm/Kittm1.1Bsm
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il2rgtm1Cgn mutation (4 available); any Il2rg mutation (168 available)
Kittm1.1Bsm mutation (0 available); any Kit mutation (179 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
arrested T cell differentiation ( J:90485 )
• similar to in Il2rgtm1Cgn homozygotes, T cell development is blocked at the TN3 to TN4 stage

immune system
arrested T cell differentiation ( J:90485 )
• similar to in Il2rgtm1Cgn homozygotes, T cell development is blocked at the TN3 to TN4 stage

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory