Phenotypes Associated with This Genotype

Genotype
MGI:4358095

• Allelic Composition: Tbx10^Dc/Tbx10^Dc
• Genetic Background: DC/LeJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

bilateral cleft upper lip ( J:89946 )

• bilateral cleft lip evident at embryonic day 16.5

cleft secondary palate ( J:89946 )

• accompanies cleft lip and evident at embryonic day 16.5

failure of palatal shelf elevation ( J:89946 )

• at E16.5, palatal shelves fail to elevate

digestive/alimentary system

cleft secondary palate ( J:89946 )

• accompanies cleft lip and evident at embryonic day 16.5

failure of palatal shelf elevation ( J:89946 )

• at E16.5, palatal shelves fail to elevate

vision/eye

delayed eyelid fusion ( J:89946 )

eyelids open at birth ( J:89946 )

• in some homozygotes

growth/size/body

bilateral cleft upper lip ( J:89946 )

• bilateral cleft lip evident at embryonic day 16.5

cleft secondary palate ( J:89946 )

• accompanies cleft lip and evident at embryonic day 16.5

failure of palatal shelf elevation ( J:89946 )

• at E16.5, palatal shelves fail to elevate