Analysis Tools
immune system
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• minimal numbers of double positive thymocytes enter into the cell cycle during the double positive stage
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• thymocytes fail to express an alphabeta TCR
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• there is a partial block in development in the DN3 stage that is more severe in the double homozygote null mice than in the singly- homozygote null mice
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• there is a partial block in development in the DN3 stage that leads to a higher percentage of these thymocytes
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• double-positive thymocytes are almost absent from the thymus in 6 week old mice
• the double-positive thymocyte population is slightly larger by nine weeks of age
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hematopoietic system
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• minimal numbers of double positive thymocytes enter into the cell cycle during the double positive stage
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• thymocytes fail to express an alphabeta TCR
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• there is a partial block in development in the DN3 stage that is more severe in the double homozygote null mice than in the singly- homozygote null mice
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• there is a partial block in development in the DN3 stage that leads to a higher percentage of these thymocytes
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• double-positive thymocytes are almost absent from the thymus in 6 week old mice
• the double-positive thymocyte population is slightly larger by nine weeks of age
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endocrine/exocrine glands
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• minimal numbers of double positive thymocytes enter into the cell cycle during the double positive stage
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