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Phenotypes Associated with This Genotype
Genotype
MGI:4355893
Allelic
Composition		 Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(3Cd1d2-Cd1d1)1Sbp mutation (2 available); any Del(3Cd1d2-Cd1d1)1Sbp mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased NK T cell number ( J:151699 )
• Valpha14 invariant NK T cell numbers are not found in these mice
abnormal dendritic cell antigen presentation ( J:151699 )
• dendritic cells loaded with alphaGal-Cer are defective in activating wild-type Valpha14 invariant NKT cells

hematopoietic system
decreased NK T cell number ( J:151699 )
• Valpha14 invariant NK T cell numbers are not found in these mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory