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Phenotypes Associated with This Genotype
Genotype
MGI:4355662
Allelic
Composition		 Crtc2tm1.1Khk/Crtc2tm1.1Khk
Genetic
Background		 involves: C57BL/6 * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crtc2tm1.1Khk mutation (0 available); any Crtc2 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal glucose homeostasis ( J:151618 )
• following glucagon stimulation, isolated hepatocytes exhibit reduced glucose secretion compared with similarly treated wild-type cells
decreased glycogen level ( J:151618 )
• in liver and muscle cells of fed mice

liver/biliary system
abnormal liver physiology ( J:151618 )
• following glucagon stimulation, isolated hepatocytes exhibit reduced glucose secretion compared with similarly treated wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory