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Phenotypes Associated with This Genotype
Genotype
MGI:4355517
Allelic
Composition		 Msh2tm1Rak/Msh2tm1Rak
Xpctm1Ecf/Xpctm1Ecf
Genetic
Background		 involves: 129P2/OlaHsd * SKH1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msh2tm1Rak mutation (1 available); any Msh2 mutation (94 available)
Xpctm1Ecf mutation (1 available); any Xpc mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell cycle ( J:94447 )
• fewer epidermal cells accumulate in S-phase and in G2-phase after treatment with 500J/m2 of UV radiation than in mice carrying Xpctm1Ecf alone

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory