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Phenotypes Associated with This Genotype
Genotype
MGI:4354299
Allelic
Composition
Afdntm2Ytk/Afdntm2Ytk
Tg(Camk2a-cre)1Gsc/0
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Afdntm2Ytk mutation (0 available); any Afdn mutation (82 available)
Tg(Camk2a-cre)1Gsc mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• the number of puncta adherentia junctions per bouton is decreased compared to in wild-type mice
• the number of perforated synapses is increased compared to in wild-type mice
• however, the number of postsynaptic densities per bouton is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory