Phenotypes Associated with This Genotype

Genotype
MGI:4354175

• Allelic Composition: Tg(Apoe-Fgf21)1Sakl/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased oxygen consumption ( J:150831 )

• hepatic oxygen consumption is increased in fasting mice compared with wild-type mice

• however, hepatic oxygen consumption under fed condition is normal

abnormal gluconeogenesis ( J:150831 )

• under fed conditions, liver gluconeogenesis is increased 60% compared to in similarly treated wild-type mice

• however, liver gluconeogenesis does not increase further under fasting conditions

increased liver glycogen level ( J:150831 )

• liver glycogen content increased 50% compared to in wild-type mice

liver/biliary system

increased liver glycogen level ( J:150831 )

• liver glycogen content increased 50% compared to in wild-type mice