Analysis Tools
hearing/vestibular/ear
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• outer hair cell bundles for loose U-shaped bundles rather than the precise V shape found in wild-type mice
• inner hair cell bundles are smaller and more widely separated than in wild-type mice
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• at 4 weeks
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• mice exhibit degeneration of outer hair cells in the middle and basal turns unlike in wild-type mice
• however, most inner hair cells remain intact
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• at 4 weeks
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• the threshold of compound action potentials is raised by about 60 dB compared to in wild-type mice
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behavior/neurological
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• mice exhibit a progressive lose of Preyer reflex between 4 and 6 weeks
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nervous system
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• outer hair cell bundles for loose U-shaped bundles rather than the precise V shape found in wild-type mice
• inner hair cell bundles are smaller and more widely separated than in wild-type mice
|
|
• at 4 weeks
|
|
• mice exhibit degeneration of outer hair cells in the middle and basal turns unlike in wild-type mice
• however, most inner hair cells remain intact
|
|
• at 4 weeks
|
|
• the threshold of compound action potentials is raised by about 60 dB compared to in wild-type mice
|
