Phenotypes Associated with This Genotype

Genotype
MGI:4353999

• Allelic Composition: Szt2^Gt(XH662)Byg/Szt2^Gt(XH662)Byg
• Genetic Background: 129S1.129P2(B6)-Szt2^Gt(XH662)Byg/FrkJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:150942 )

• when examined at weaning only about 10% of the expected number of homozygotes are found

preweaning lethality, incomplete penetrance ( J:150942 )

• when examined at weaning only about 10% of the expected number of homozygotes are found

behavior/neurological

maximal tonic hindlimb extension seizures ( J:150942 )

• several mice went past the minimal clonic seizure endpoint proceeding directly to tonic hindlimb extension

minimal clonic seizures ( J:150942 )

• increased sensitivity to electrically induced minimal clonic seizures

pigmentation

diluted coat color ( J:150942 )

• slightly diluted coat color

nervous system

maximal tonic hindlimb extension seizures ( J:150942 )

• several mice went past the minimal clonic seizure endpoint proceeding directly to tonic hindlimb extension

minimal clonic seizures ( J:150942 )

• increased sensitivity to electrically induced minimal clonic seizures

integument

diluted coat color ( J:150942 )

• slightly diluted coat color