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Phenotypes Associated with This Genotype
Genotype
MGI:4353998
Allelic
Composition		 Szt2m1Frk/Szt2m1Frk
Genetic
Background		 involves: BALB/cByJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Szt2m1Frk mutation (2 available); any Szt2 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased susceptibility to pharmacologically induced seizures ( J:150942 )
• shorter latency to PTZ-induced tonic-clonic seizures compared to controls
minimal clonic seizures ( J:150942 )
• increased sensitivity to electrically induced minimal clonic seizures
tonic-clonic seizures ( J:150942 )
• shorter latency to PTZ-induced tonic-clonic seizures compared to controls

nervous system
increased susceptibility to pharmacologically induced seizures ( J:150942 )
• shorter latency to PTZ-induced tonic-clonic seizures compared to controls
minimal clonic seizures ( J:150942 )
• increased sensitivity to electrically induced minimal clonic seizures
tonic-clonic seizures ( J:150942 )
• shorter latency to PTZ-induced tonic-clonic seizures compared to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory