Phenotypes Associated with This Genotype

Genotype
MGI:4353997

• Allelic Composition: Szt2^m1Frk/Szt2^m1Frk
• Genetic Background: C57BL/6J-Szt2^m1Frk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:150942 )

N • no motor abnormalities are detected

abnormal kindling response ( J:150942 )

• decrease in the latency to first seizure in males compared to controls using a repetitive non-invasive kindling assay

minimal clonic seizures ( J:150942 )

• increased sensitivity to electrically induced minimal clonic seizures

• however, mice do not exhibit spontaneous or handling provoked seizures

nervous system

nervous system phenotype ( J:150942 )

N • no electroencephalographic or neurosensory abnormalities are detected

abnormal kindling response ( J:150942 )

• decrease in the latency to first seizure in males compared to controls using a repetitive non-invasive kindling assay

minimal clonic seizures ( J:150942 )

• increased sensitivity to electrically induced minimal clonic seizures

• however, mice do not exhibit spontaneous or handling provoked seizures