liver/biliary system
• IgA levels in the bile are 3.5-fold lower than in controls
• the IgA present in the bile is mostly in a monomer state compared to the dimeric state that predominates in wild-type bile
|
immune system
• production of dimeric IgA is severely curtailed in these mice
|
• serum IgA levels are about 35-fold higher
(J:34042)
• IgA levels found in bronchoalveolar lavage fluid are 8- to 18- fold higher than in controls
(J:34042)
• IgA is often in monomeric form in the serum and mucosal fluids
(J:34042)
• IgA levels in mucosal secretions and breast milk are not significantly different from controls
(J:34042)
• serum IgA levels are over 30-fold higher than in controls
(J:75843)
• monomer to dimer is 10:1 ratio compared to 1:1 in wild-type
(J:75843)
|
digestive/alimentary system
• while levels of IgA are normal in intestinal fluids, monomeric forms of IgA are found in these fluids that are not found in wild-type controls
(J:34042)
• fecal levels of IgA are 5.5-fold lower than in controls
(J:75843)
|
endocrine/exocrine glands
• monomeric forms of IgA are found in the breast milk while the dimeric form of IgA predominates in wild-type breast milk
|
integument
• monomeric forms of IgA are found in the breast milk while the dimeric form of IgA predominates in wild-type breast milk
|
hematopoietic system
• production of dimeric IgA is severely curtailed in these mice
|
• serum IgA levels are about 35-fold higher
(J:34042)
• IgA levels found in bronchoalveolar lavage fluid are 8- to 18- fold higher than in controls
(J:34042)
• IgA is often in monomeric form in the serum and mucosal fluids
(J:34042)
• IgA levels in mucosal secretions and breast milk are not significantly different from controls
(J:34042)
• serum IgA levels are over 30-fold higher than in controls
(J:75843)
• monomer to dimer is 10:1 ratio compared to 1:1 in wild-type
(J:75843)
|