Analysis Tools
reproductive system
growth/size/body
|
• at P19, body weight is reduced 30% compared to in wild-type mice
• regardless of reduced suckling competition, mice weigh 25% less than wild-type at P10 and P18
• however, by P60 mice have normal body weight
|
cellular
|
• proliferation of E12.5 mouse embryonic fibroblast is reduced compared to wild-type cells
|
|
• mouse embryonic fibroblasts achieve senescence at passage 3 unlike wild-type cells that do so at passage 5
|
limbs/digits/tail
kinked tail
(
J:151280
)
|
• in one third of mice
|
