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Phenotypes Associated with This Genotype
Genotype
MGI:4353640
Allelic
Composition		 Gt(ROSA)26Sortm8(RNAi:Crhr1)Rkuhn/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm8(RNAi:Crhr1)Rkuhn mutation (0 available); any Gt(ROSA)26Sor mutation (1095 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased anxiety-related response ( J:151155 )
• mice spend more time in an averse lit compartment than wild-type mice

homeostasis/metabolism
decreased circulating corticosterone level ( J:151155 )
• compared to wild-type mice following 10 minute restraint stress

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory