About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4353392
Allelic
Composition		 Tg(CD2-Zbtb7b)C8Rbo/?
Themistm1Lov/Themistm1Lov
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CD2-Zbtb7b)C8Rbo mutation (0 available)
Themistm1Lov mutation (0 available); any Themis mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell differentiation ( J:151075 )
• CD8 single positive thymocytes fail to develop in these mice
• transgene expression fails to alleviate the partial block in CD4 development

hematopoietic system
abnormal T cell differentiation ( J:151075 )
• CD8 single positive thymocytes fail to develop in these mice
• transgene expression fails to alleviate the partial block in CD4 development

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory