Phenotypes Associated with This Genotype

Genotype
MGI:4353224

• Allelic Composition: Arx^tm1.1Jno/Arx^tm1.1Jno
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

myoclonus ( J:151082 )

♀ • at P7 the incidence of high amplitude movements including sustained spasm-like movements strong enough to cause the pup to flip over, axial contractions that bow or twist the body, and abrupt lateral displacements, is increased

♀ • the frequency of these high amplitude movements decreases between P9 and P11

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:151082 )

♀N • unlike null mice, no abnormalities in pancreatic morphology or physiology are detected

muscle

myoclonus ( J:151082 )

♀ • at P7 the incidence of high amplitude movements including sustained spasm-like movements strong enough to cause the pup to flip over, axial contractions that bow or twist the body, and abrupt lateral displacements, is increased

♀ • the frequency of these high amplitude movements decreases between P9 and P11

nervous system

myoclonus ( J:151082 )

♀ • at P7 the incidence of high amplitude movements including sustained spasm-like movements strong enough to cause the pup to flip over, axial contractions that bow or twist the body, and abrupt lateral displacements, is increased

♀ • the frequency of these high amplitude movements decreases between P9 and P11