Phenotypes for H2 Themis MGI:4353112 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	H2^b/H2^d Themis^tm1Gasc/Themis^tm1Gasc
Genetic Background	involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2^b mutation (28 available); any H2 mutation (280 available)
H2^d mutation (23 available); any H2 mutation (280 available)
Themis^tm1Gasc mutation (1 available); any Themis mutation (55 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal negative T cell selection ( J:151074 )

• superantigen-mediated deletion of T cells expressing Vbeta5, Vbeta11, and Vbeta12 is less efficient in these mice

immune system

abnormal negative T cell selection ( J:151074 )

• superantigen-mediated deletion of T cells expressing Vbeta5, Vbeta11, and Vbeta12 is less efficient in these mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23