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Phenotypes Associated with This Genotype
Genotype
MGI:3852066
Allelic
Composition
Per2tm1Drw/Per2tm1Drw
Genetic
Background
involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Per2tm1Drw mutation (2 available); any Per2 mutation (73 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• all mice become arrhythmic when transferred into dark-dark conditions although at different duration and extent of rhythm persistence
• at the midday 3-hour period, mice wake more than wild-type mice
• at midday, mice exhibit less REM sleep than wild-type mice
• during the 12-hour recovery after 6 hours of prolonged waking, mice exhibit less waking and more short wave sleep compared to similarly treated wild-type mice
• mice are awake more during the mid-third of the light period compared with wild-type mice

homeostasis/metabolism
• the acrophase of core temperature is phase-advanced compared to in wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory