Phenotypes Associated with This Genotype

Genotype
MGI:3851788

• Allelic Composition: Tg(Myh6-Mef2c)2Jmol/0; Tg(Myh6-Ppp3ca)37Eno/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart atrium morphology ( J:111573 )

• mice show large atrial clots

cardiac hypertrophy ( J:111573 )

• cardiac hypertrophy is not enhanced above that observed in Tg(Myh6-Mef2c)2Jmol single transgenic animals

decreased cardiac muscle contractility ( J:111573 )

• degree of functional decompensation is not enhanced compared to Tg(Myh6-Mef2c)2Jmol single transgenic mice

muscle

decreased cardiac muscle contractility ( J:111573 )

• degree of functional decompensation is not enhanced compared to Tg(Myh6-Mef2c)2Jmol single transgenic mice

growth/size/body

cardiac hypertrophy ( J:111573 )

• cardiac hypertrophy is not enhanced above that observed in Tg(Myh6-Mef2c)2Jmol single transgenic animals