Analysis Tools
endocrine/exocrine glands
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• at P9 Sertoli cells are randomly distributed unlike in controls
• at P14 tubules lack luminal space and are instead filled with a poorly organized mix of Sertoli cells and differentiating germ cells
• at P28 tubules contain no apparent germ cells and are filled with randomized, unpolarized Sertoli cells with immature morphology
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• Sertoli cells fail to migrate properly and retain an immature morphology at P28
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reproductive system
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• by P9 the distribution of germs cells is highly abnormal with more cells in the center and fewer cells at the periphery of the tubules
• meiosis initiates but germ cells are absent by P28
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• at P9 Sertoli cells are randomly distributed unlike in controls
• at P14 tubules lack luminal space and are instead filled with a poorly organized mix of Sertoli cells and differentiating germ cells
• at P28 tubules contain no apparent germ cells and are filled with randomized, unpolarized Sertoli cells with immature morphology
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• Sertoli cells fail to migrate properly and retain an immature morphology at P28
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cellular
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• by P9 the distribution of germs cells is highly abnormal with more cells in the center and fewer cells at the periphery of the tubules
• meiosis initiates but germ cells are absent by P28
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