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Phenotypes Associated with This Genotype
Genotype
MGI:3851502
Allelic
Composition		 Ephb1tm1Cmn/Ephb1tm1Cmn
Ephb2tm1Paw/Ephb2tm1Paw
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ephb1tm1Cmn mutation (1 available); any Ephb1 mutation (42 available)
Ephb2tm1Paw mutation (1 available); any Ephb2 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon pruning ( J:150550 )
• mossy fiber pruning is defective
abnormal axon morphology ( J:150550 )
• infra-pyramidal bundle (IPB) axons are longer than in wild-type mice

cellular
abnormal axon pruning ( J:150550 )
• mossy fiber pruning is defective

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory