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Phenotypes Associated with This Genotype
Genotype
MGI:3851402
Allelic
Composition		 Wt1tm1(EGFP/cre)Wtp/Wt1+
Zfpm2tm1Sho/Zfpm2tm2Sho
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wt1tm1(EGFP/cre)Wtp mutation (1 available); any Wt1 mutation (34 available)
Zfpm2tm1Sho mutation (2 available); any Zfpm2 mutation (48 available)
Zfpm2tm2Sho mutation (1 available); any Zfpm2 mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, complete penetrance ( J:150452 )
• pups die in perinatal period

cardiovascular system
cardiovascular system phenotype ( J:150452 )
N
• coronary vascular development is not impaired
thin myocardium compact layer ( J:150452 )
• compact myocardium is thin
abnormal atrioventricular cushion morphology ( J:150452 )
• severe atrio-ventricular endocardial cushion defect is observed by E14.5

muscle
thin myocardium compact layer ( J:150452 )
• compact myocardium is thin

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory