Analysis Tools
mortality/aging
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• affected mice die by 5 months of age
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growth/size/body
ovary cyst
(
J:14466
)
 |
|
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• continued growth differential likely due to kidney abnormalities
|
kidney cyst
(
J:14466
)
skeleton
|
• Background Sensitivity: seen in all affected mice but severity depends on genetic background
|
rib fusion
(
J:14466
)
|
• unilateral and bilateral fusions occur at 12, 13, 14
|
|
• Background Sensitivity: may involve the 18th -29th
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• fusions at 5, 6
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• fusions at 4, 5
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reproductive system
 |
• unstimulated and may be displaced from expected location
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ovary cyst
(
J:14466
)
|
|
|
small testis
(
J:14466
)
|
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• a testis may be small or absent
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cryptorchism
(
J:14466
)
|
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• one or both testis may be retained in the body cavity
|
endocrine/exocrine glands
|
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• unstimulated and may be displaced from expected location
|
ovary cyst
(
J:14466
)
|
|
|
small testis
(
J:14466
)
|
|
• a testis may be small or absent
|
cryptorchism
(
J:14466
)
|
|
• one or both testis may be retained in the body cavity
|
renal/urinary system
kidney cyst
(
J:14466
)
small kidney
(
J:14466
)
hydroureter
(
J:14466
)
limbs/digits/tail
|
• Background Sensitivity: seen in all affected mice but severity depends on genetic background
|
kinked tail
(
J:14466
)
behavior/neurological
head shaking
(
J:14466
)
|
• mild head-tossing noted
|
integument
|
• narrower in diameter than normal
|
