Phenotypes Associated with This Genotype

Genotype
MGI:3851331

• Allelic Composition: Cacna1g^tm1Dgen/Cacna1g^tm1Dgen
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

hyperactivity ( J:150571 )

• there are slight increases in activity in the wake period though not enough to explain resistance to obesity

growth/size/body

decreased susceptibility to diet-induced obesity ( J:150571 )

• mice resist weight gain induced by a high fat diet

• wild-type mice have 12.8 g of fat after the study compared to 7.7 g in mutant mice

• wild-type mice have 33.6 % bodyfat compared to 23.8% in mutant mice

homeostasis/metabolism

decreased susceptibility to diet-induced obesity ( J:150571 )

• mice resist weight gain induced by a high fat diet

• wild-type mice have 12.8 g of fat after the study compared to 7.7 g in mutant mice

• wild-type mice have 33.6 % bodyfat compared to 23.8% in mutant mice