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Phenotypes Associated with This Genotype
Genotype
MGI:3850536
Allelic
Composition
Gfaptm2Mes/Gfap+
Tg(GFAP)10Mes/0
Genetic
Background
involves: 129S7/SvEvBrd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfaptm2Mes mutation (2 available); any Gfap mutation (34 available)
Tg(GFAP)10Mes mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• all animals die by under 50 days of age (most die around 30 days)

nervous system
• Rosenthal fiber formation is observed

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Alexander disease DOID:4252 OMIM:203450
J:146191


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/17/2017
MGI 6.10
The Jackson Laboratory