Phenotypes Associated with This Genotype

Genotype
MGI:3850352

• Allelic Composition: Sox18^tm1Koop/Sox18^tm1Koop
• Genetic Background: B6.129-Sox18^tm1Koop

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:143564 )

• mice die before E14.5

homeostasis/metabolism

skin edema ( J:143564 )

immune system

abnormal lymphatic vessel morphology ( J:143564 )

• lymphatic vessels are finer, denser, and more branched with more loops and fewer blind-ended sacs compared to in wild-type mice

integument

skin edema ( J:143564 )