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Phenotypes Associated with This Genotype
Genotype
MGI:3850092
Allelic
Composition
Sun1tm1Mhan/Sun1tm1Mhan
Sun2tm1Mhan/Sun2tm1Mhan
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sun1tm1Mhan mutation (1 available); any Sun1 mutation (61 available)
Sun2tm1Mhan mutation (1 available); any Sun2 mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice die soon after birth
• however, neural expression of Unc84b rescues neonatal lethality

muscle
• 81% of muscle cells have no nuclei beneath neuromuscular junctions unlike in wild-type mice

growth/size/body
• reduced body size at birth

homeostasis/metabolism
• at birth


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory