About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3850051
Allelic
Composition		 Nlrp3tm2Hhf/Nlrp3+
Tg(CAG-cre/Esr1*)5Amc/?
Genetic
Background		 involves: 129/Sv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrp3tm2Hhf mutation (1 available); any Nlrp3 mutation (69 available)
Tg(CAG-cre/Esr1*)5Amc mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
slow postnatal weight gain ( J:150054 )
• some older mice have slower weight gain

immune system
skin inflammation ( J:150054 )
• some older mice develop skin inflammation suggesting leaky expression of the cre recombinase

integument
skin inflammation ( J:150054 )
• some older mice develop skin inflammation suggesting leaky expression of the cre recombinase

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory