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Phenotypes Associated with This Genotype
Genotype
MGI:3849035
Allelic
Composition		 Cdh23ahl/Cdh23ahl
Genetic
Background		 C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh23ahl mutation (51 available); any Cdh23 mutation (274 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
organ of Corti degeneration ( J:87783 )
• in 3 of 4 cochleae assesed at 12 months of age the organ of Corti had totally degenerated

nervous system
cochlear ganglion hypoplasia ( J:87783 )
• at 9 months of age there is a decrease in the ganglion cell density for each turn over time with the largest cell loss in the basal turn

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory