Phenotypes Associated with This Genotype

Genotype
MGI:3848988

• Allelic Composition: Fmn1^tm2Made/Fmn1^tm2Made
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal autopod morphology ( J:149484 )

• autopods exhibit a loss of a digit and soft tissue fusion of the middle digits unlike in wild-type mice

• hindlimb autopods exhibit a metatarsal fusion of the two posterior digits unlike in wild-type mice

oligodactyly ( J:149484 )

• 66% of mice exhibit reduced digit number to four in both the forelimb and hindlimb

absent fibula ( J:149484 )

fused metatarsal bones ( J:149484 )

• in the hindlimb

renal/urinary system

single kidney ( J:149484 )

• 4.4% of mice exhibit unilateral renal aplasia unlike in wild-type mice

skeleton

absent fibula ( J:149484 )

fused metatarsal bones ( J:149484 )

• in the hindlimb