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Phenotypes Associated with This Genotype
Genotype
MGI:3848912
Allelic
Composition
Gt(ROSA)26Sortm5(Etv4/en,-GFP)Amc/Gt(ROSA)26Sor+
Tg(Prrx1-cre)1Cjt/0
Genetic
Background
involves: 129 * C57BL/6 * CBA * SJL/J * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm5(Etv4/en,-GFP)Amc mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• less well-formed ectopic cartilaginous elements are observed in the anterior limb unlike in wild-type mice
• the most anterior digit contains three phalanges instead of the normal two
• mice have 6 to 7 digits unlike in wild-type mice
• in some cases, the ectopic digit is more centrally located and consists of three phalangeal elements without an additional metacarpal element

skeleton
• the most anterior digit contains three phalanges instead of the normal two


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory