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Phenotypes Associated with This Genotype
Genotype
MGI:3848833
Allelic
Composition
Chattm2(cre)Lowl/Chat+
Mapttm3(Sema3e)Arbr/Mapttm3(Sema3e)Arbr
Genetic
Background
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chattm2(cre)Lowl mutation (4 available); any Chat mutation (57 available)
Mapttm3(Sema3e)Arbr mutation (0 available); any Mapt mutation (428 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• 23% of triceps motor neurons receive monosynaptic input from triceps afferents compared to 95% in wild-type mice
• however, triceps and cutaneous maximus motor neurons normally lack monosynaptic input from cutaneous maximus afferents

behavior/neurological
N
• mice exhibit no behavior deficits


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory