Phenotypes Associated with This Genotype

Genotype
MGI:3848831

• Allelic Composition: Sema3e^{tm1(cre/ERT2)Arbr}/Sema3e^{tm1(cre/ERT2)Arbr}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:149553 )

N • mice exhibit normal positions of the cell bodies and dendrites of cutaneous maximus or triceps motor neurons

abnormal motor neuron morphology ( J:149553 )

• mice exhibit a 3-fold increase in the number of proprioceptive synaptic contacts with identified cutaneous maximus motor neurons compared to in wild-type mice

abnormal motor neuron innervation pattern ( J:149553 )

• 45% of cutaneous motor neurons receive monosynaptic input after stimulation of cutaneous maximus afferents unlike wild-type motor neurons

• however, monosynaptic specificity from the tricep is normal

behavior/neurological

behavior/neurological phenotype ( J:149553 )

N • mice exhibit no behavior deficits