Phenotypes Associated with This Genotype

Genotype
MGI:3848612

• Allelic Composition: Tg(GAS7)63.2Lus/0
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:148831 )

• males have significantly decreased body weight

adipose tissue

abnormal adipose tissue amount ( J:148831 )

• males have a significantly reduced fat/lean ratio (males show increased adiposity relative to females)

• difference in adiposity is first detected at 11 weeks of age in males

decreased gonadal fat pad weight ( J:148831 )

decreased mesenteric fat pad weight ( J:148831 )

• observed in females

decreased total fat pad weight ( J:148831 )

• significant in males

homeostasis/metabolism

decreased circulating glucose level ( J:148831 )

• males show reduced glucose levels

abnormal cholesterol level ( J:148831 )

• significantly reduced unesterified cholesterol level in males and females

increased cholesterol level ( J:148831 )

• males show significantly increased total cholesterol levels and high-density lipoprotein (HDL) levels

decreased triglyceride level ( J:148831 )

• significantly reduced in males