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Phenotypes Associated with This Genotype
Genotype
MGI:3848508
Allelic
Composition		 Six2tm1Gco/Six2tm1Gco
Wnt9btm1.1Amc/Wnt9btm1.1Amc
Genetic
Background		 involves: 129/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Six2tm1Gco mutation (0 available); any Six2 mutation (15 available)
Wnt9btm1.1Amc mutation (0 available); any Wnt9b mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal kidney development ( J:148455 )
• at 12.5 dpc, the amount of cap mesenchyme is greatly reduced
delayed kidney development ( J:148455 )
• no renal vesicle formation is observed at 12.5 dpc
• ingrowth of the ureteric bud is delayed compared to controls at 11.5 dpc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory