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Phenotypes Associated with This Genotype
Genotype
MGI:3848223
Allelic
Composition
Tdo2chky/Tdo2chky
Tyrc/Tyrc
Genetic
Background
STOCK Tdo2chky/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tdo2chky mutation (1 available); any Tdo2 mutation (38 available)
Tyrc mutation (79 available); any Tyr mutation (382 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Pale yellow coat and cataracts in the Tdo2chky/Tdo2chky Tyrc/Tyrc mouse

pigmentation
• on an albino background mice homozygous for the chick yellow mutation have a slightly yellow coat color, which is evident by approximately 10 days of age when the first coat comes in

vision/eye
• very early signs of cataracts are found at one month of age, lens extrusion and early signs of cataracts are found at 3 months of age, and retinal degeneration and cataracts are found at 7 months of age and thereafter

integument
• on an albino background mice homozygous for the chick yellow mutation have a slightly yellow coat color, which is evident by approximately 10 days of age when the first coat comes in


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory