Phenotypes Associated with This Genotype

Genotype
MGI:3848028

• Allelic Composition: Timm23^{Gt(W023C08)Wrst}/Timm23⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:149173 )

• mortality up to 9 months of age is increased compared to in wild-type mice

premature aging ( J:149173 )

• mice exhibit symptoms of premature aging including alopecia and kyphosis

behavior/neurological

impaired coordination ( J:149173 )

• male mice spend less time on a rotarod compared with wild-type mice

decreased grip strength ( J:149173 )

• grip strength is decreased in female mice compared to with wild-type mice

skeleton

kyphosis ( J:149173 )

integument

alopecia ( J:149173 )