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Phenotypes Associated with This Genotype
Genotype
MGI:3846578
Allelic
Composition		 Fat4tm1.1Hmc/Fat4tm1.1Hmc
Vangl2Lp/Vangl2+
Genetic
Background		 involves: 129P2/OlaHsd * A * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fat4tm1.1Hmc mutation (1 available); any Fat4 mutation (224 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
kidney cyst ( J:138247 )
• increase in the severity of cystic tubules compared to mice homozygous for Fat4tm1.1Hmc alone

growth/size/body
kidney cyst ( J:138247 )
• increase in the severity of cystic tubules compared to mice homozygous for Fat4tm1.1Hmc alone

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory