Phenotypes Associated with This Genotype

Genotype
MGI:3845974

• Allelic Composition: Fcer2a^tm1Putt/Fcer2a^tm1Putt
• Genetic Background: involves: 129S/SvEv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal B cell proliferation ( J:69547 )

• B cell proliferation in response to BCR stimulation is reduced by about 25%

• no significant differences in activation occur when CD40 co-stimulation is performed

hematopoietic system

abnormal B cell proliferation ( J:69547 )

• B cell proliferation in response to BCR stimulation is reduced by about 25%

• no significant differences in activation occur when CD40 co-stimulation is performed

cellular

abnormal B cell proliferation ( J:69547 )

• B cell proliferation in response to BCR stimulation is reduced by about 25%

• no significant differences in activation occur when CD40 co-stimulation is performed