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Phenotypes Associated with This Genotype
Genotype
MGI:3844994
Allelic
Composition		 Mapttm2(Hdac1)Jae/Mapttm2(Hdac1)Jae
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapttm2(Hdac1)Jae mutation (0 available); any Mapt mutation (453 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal hippocampus pyramidal cell morphology ( J:148391 )
• the overall level of acetylated lysine on histones is decreased in these neurons compared to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory