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Phenotypes Associated with This Genotype
Genotype
MGI:3844640
Allelic
Composition		 Gt(ROSA)26Sortm2(Nfatc2*)Rao/Gt(ROSA)26Sor+
Tg(CMV-cre)1Cgn/0
Genetic
Background		 involves: BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(Nfatc2*)Rao mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(CMV-cre)1Cgn mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:148341 )
• fewer than expected mice with this genotype are found

hematopoietic system
abnormal hematopoietic system morphology/development ( J:148341 )
• the fraction of B and T cells expressing the recombined allele decreases during differentiation and maturation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory