Analysis Tools
nervous system
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• loss of extrasynaptic alpha5GABAa receptors in CA1 pyramidal cells
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• lower prepulse inhibition at all prepulse intensities tested
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behavior/neurological
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• mice suffer less impairment to their ability to grasp a wire after treatment with diazepam
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• in 1 second trace fear conditioning tests, mice display greater retention of the conditioned response when retested 48 hours later
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• lower water consumption
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• increased distance travelled in an open field test
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