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Phenotypes Associated with This Genotype
Genotype
MGI:3843303
Allelic
Composition
Braftm1Cpri/Braftm1Cpri
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Braftm1Cpri mutation (0 available); any Braf mutation (58 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• serum starved and replete recombined mouse embryonic fibroblasts (MEFs) display increased proliferation with 9.57% and 26.2% of cells entering S-phase, respectively, compared to 6.75% and 11.5% for starved and fed wild-type cells, respectively
• recombined MEFs can also grow at higher densities and lose contact inhibition


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory