Phenotypes Associated with This Genotype

Genotype
MGI:3843022

• Allelic Composition: Vpreb1a^tm1Ilm/Vpreb1a^tm1Ilm; Vpreb1b^tm1Ilm/Vpreb1b⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased mature B cell number ( J:104211 )

• B220+ IgM+ cells reduced about 75%

decreased pre-B cell number ( J:104211 )

• pre-BII cells reduced about 75%

• ratio of large to small pre-BII cells is normal

increased pre-B cell number ( J:104211 )

• pre-BI cell numbers are increased about 2 fold

hematopoietic system

decreased mature B cell number ( J:104211 )

• B220+ IgM+ cells reduced about 75%

decreased pre-B cell number ( J:104211 )

• pre-BII cells reduced about 75%

• ratio of large to small pre-BII cells is normal

increased pre-B cell number ( J:104211 )

• pre-BI cell numbers are increased about 2 fold