Phenotypes for Ache Prima1 MGI:3842461 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ache^tm4Pata/Ache^tm4Pata Prima1^tm1Vebe/Prima1^tm1Vebe
Genetic Background	involves: 129X1/SvJ * C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ache^tm4Pata mutation (0 available); any Ache mutation (31 available)
Prima1^tm1Vebe mutation (0 available); any Prima1 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body weight ( J:147425 )

• mice exhibit decreased body weight compared to wild type mice

• however, weight loss can be reduced with a supplemental diet

homeostasis/metabolism

abnormal body temperature homeostasis ( J:147425 )

• mice exhibit postnatal thermoregulation defects

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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