Phenotypes for Smo Tulp3 MGI:3842142 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Smo^tm1Amc/Smo^tm1Amc Tulp3^hhkr/Tulp3^hhkr
Genetic Background	involves: 129X1/SvJ * C3H/HeH * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smo^tm1Amc mutation (1 available); any Smo mutation (39 available)
Tulp3^hhkr mutation (1 available); any Tulp3 mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal neural tube morphology ( J:147584 )

• expression of neural tube markers is ventralized compared to in wild-type mice

increased spinal cord size ( J:147584 )

• mice exhibit an expansion of the caudal spinal cord unlike in wild-type mice

cardiovascular system

pericardial edema ( J:147584 )

homeostasis/metabolism

pericardial edema ( J:147584 )

embryo

abnormal neural tube morphology ( J:147584 )

• expression of neural tube markers is ventralized compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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