Phenotypes Associated with This Genotype

Genotype
MGI:3841466

• Allelic Composition: Ksr1^tm1Shaw/Ksr1^tm1Shaw
• Genetic Background: involves: DBA/1LacJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased white fat cell number ( J:100406 )

• identical fat pad weights suggest mice have fewer but larger adipocytes

increased fat cell size ( J:100406 )

• marked increase in cross sectional area of adipocytes in epididymal fat tissue

cellular

abnormal cell differentiation ( J:100406 )

• MEFs treated with an adipogenic cocktail fail to differentiate into adipocytes