About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3841388
Allelic
Composition		 Mplhlb219/Mpl+
Genetic
Background		 C57BL/6J-Mplhlb219/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mplhlb219 mutation (2 available); any Mpl mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal definitive hematopoiesis ( J:146577 )
• mutant mice exhibit a significant increase in the progenitor CFU-GM, CFU-M, and CFU-Mk populations compared to controls
decreased erythrocyte cell number ( J:146577 )
• significantly fewer red blood cells compared to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory