Phenotypes Associated with This Genotype

Genotype
MGI:3841386

• Allelic Composition: Bptf^tm1.2Cwu/Bptf^tm1.2Cwu
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:147414 )

• embryonic lethality occurs between E7.5 and E8.5

embryo

abnormal ectoderm development ( J:147414 )

• cultured embryoid bodies fail to form more differentiated ectoderm

abnormal endoderm development ( J:147414 )

• cultured embryoid bodies fail to form an endoderm

decreased embryo size ( J:147414 )

• ES cells cultured in vitro from smaller embryoid bodies than controls

absent mesoderm ( J:147414 )

• cultured embryoid bodies fail to form an mesoderm

growth/size/body

decreased embryo size ( J:147414 )

• ES cells cultured in vitro from smaller embryoid bodies than controls